STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADI32655.1TIGRFAM: pyruvate kinase; KEGG: pca:Pcar_2983 pyruvate kinase; PFAM: Pyruvate kinase barrel; Belongs to the pyruvate kinase family. (469 aa)    
Predicted Functional Partners:
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 0.987
ADI32408.1
TIGRFAM: bifunctional phosphoglucose/phosphomannose isomerase; PFAM: Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase-like; sugar isomerase (SIS).
  
 
 0.956
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 
 0.928
ADI31798.1
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
   
 0.927
ADI32104.1
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: ppd:Ppro_0325 thiamine pyrophosphate binding domain-containing protein.
  
 0.923
ADI32111.1
KEGG: dat:HRM2_41100 PorB3; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate protein domain protein TPP-binding.
  
 0.923
ADI32552.1
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: dol:Dole_1391 thiamine pyrophosphate binding domain-containing protein.
  
 0.923
ADI32107.1
KEGG: sfu:Sfum_2792 pyruvate/ketoisovalerate oxidoreductase, gamma subunit; TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase.
   
 0.921
ADI32549.1
TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; KEGG: sfu:Sfum_0543 pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase.
   
 0.921
ADI31595.1
KEGG: maq:Maqu_0971 oxaloacetate decarboxylase; TIGRFAM: oxaloacetate decarboxylase alpha subunit; PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; biotin/lipoyl attachment domain-containing protein.
  
 
 0.919
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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