STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pelATranslation factor pelota; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. (356 aa)    
Predicted Functional Partners:
tuf
Translation elongation factor EF-1, subunit alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
   
 
 0.852
ADI32652.1
ABC transporter related protein; KEGG: Os11g0546000; hypothetical protein; K06174 ATP-binding cassette, sub-family E, member 1; PFAM: ABC transporter related; 4Fe-4S ferredoxin iron-sulfur binding domain protein; metal-binding domain in RNase L inhibitor, RLI; SMART: AAA ATPase.
  
 
 0.756
eif5a
Translation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
  
 
 
 0.729
ADI32668.1
SMART: DNA-directed DNA polymerase B; TIGRFAM: DNA polymerase Pol2; KEGG: pold1; polymerase (DNA directed), delta 1, catalytic subunit 125kDa; K02327 DNA polymerase delta subunit 1; PFAM: DNA polymerase B region; DNA polymerase B exonuclease.
       0.709
ADI31695.1
TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: similar to Probable phenylalanyl-tRNA synthetase beta chain (Phenylalanine--tRNA ligase beta chain) (PheRS); K01890 phenylalanyl-tRNA synthetase beta chain; PFAM: tRNA synthetase B5; B3/4 domain protein.
 
   
 0.649
rpl29
Ribosomal protein L29; KEGG: dat:HRM2_36180 RpmC; TIGRFAM: ribosomal protein L29; PFAM: ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.
   
 
 0.643
flpA
Fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
  
 
 0.637
rps19p
Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
 
 
 
 0.584
rps3
Ribosomal protein S3; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
   
 
 0.580
rpl15e
PFAM: Ribosomal protein L15e; KEGG: Os03g0598800; hypothetical protein; K02877 large subunit ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family.
 
 
   0.568
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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