Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
spt4DNA-directed RNA polymerase subunit E, RpoE2; Stimulates transcription elongation; Belongs to the archaeal Spt4 family. (68 aa)    
Predicted Functional Partners:
spt5
NusG antitermination factor; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
  
 0.996
ADI32719.1
TIGRFAM: DNA-directed RNA polymerase; KEGG: zgc:92878; PFAM: RNA polymerase Rpb7 domain protein.
 
 
 0.996
rps27ae
PFAM: Ribosomal protein S27a; Belongs to the eukaryotic ribosomal protein eS31 family.
  
    0.952
ADI32423.1
SMART: RNA polymerase Rbp10.
   
   0.951
ADI32717.1
Protein of unknown function DUF359; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
  
    0.894
ADI32750.1
DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.870
rpoD
RNA polymerase insert; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
   0.859
rpoH
RNA polymerase Rpb5; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.
   
 
 0.858
ADI32749.1
DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.842
ADI31299.1
PFAM: RNA polymerase dimerisation; KEGG: similar to DNA-directed RNA polymerase II 13.3 kDa polypeptide (RPB11); K03008 DNA-directed RNA polymerase II subunit J.
   
 
 0.841
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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