STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADI32720.1KEGG: Protein C14orf111 homolog; PFAM: Protein of unknown function DUF652; SMART: Nucleotide binding protein PINc. (136 aa)    
Predicted Functional Partners:
ADI32450.1
TIGRFAM: KH domain protein; PFAM: K Homology, type 1, subgroup; KEGG: similar to RNA-binding protein PNO1; K11884 RNA-binding protein PNO1; SMART: KH domain protein.
  
 0.986
eif2g
Protein synthesis factor GTP-binding protein; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
  
    0.840
rps6e
PFAM: Ribosomal protein S6e; KEGG: 40S RIBOSOMAL PROTEIN S6; K02991 small subunit ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family.
 
 
 0.838
nep1
Suppressor Mra1 family protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.
   
 0.785
ADI32297.1
PFAM: Pre-mRNA processing ribonucleoprotein, binding domain protein; NOSIC domain protein; KEGG: hypothetical protein.
  
 
 0.768
ADI32719.1
TIGRFAM: DNA-directed RNA polymerase; KEGG: zgc:92878; PFAM: RNA polymerase Rpb7 domain protein.
 
  
 0.737
ADI32123.1
Hypothetical protein.
   
    0.673
ADI32694.1
Brix domain protein; Probably involved in the biogenesis of the ribosome.
  
    0.652
rps4
Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
   
 0.619
spt4
DNA-directed RNA polymerase subunit E, RpoE2; Stimulates transcription elongation; Belongs to the archaeal Spt4 family.
       0.610
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.