Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ADI32731.1PFAM: protein of unknown function DUF52; KEGG: gme:Gmet_1957 hypothetical protein; Belongs to the MEMO1 family. (289 aa)    
Predicted Functional Partners:
ADI32241.1
PFAM: AMMECR1 domain protein; KEGG: dal:Dalk_3956 AMMECR1 domain protein.
    0.983
rps2
Ribosomal protein S2; KEGG: expressed hypothetical protein; K02998 small subunit ribosomal protein SAe; TIGRFAM: ribosomal protein S2; PFAM: ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
  
    0.882
ADI32315.1
PFAM: Radical SAM domain protein; KEGG: gur:Gura_2854 radical SAM domain-containing protein.
     0.836
rpoN
RNA polymerase, N/8 Kd subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family.
       0.833
rps9
Ribosomal protein S9P; KEGG: SORBIDRAFT_05g001680; hypothetical protein; TIGRFAM: ribosomal protein S9P; PFAM: ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
  
    0.806
rpl13
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
    0.798
rpl18e
PFAM: ribosomal protein L15; KEGG: hypothetical protein; Belongs to the eukaryotic ribosomal protein eL18 family.
       0.795
rpoD
RNA polymerase insert; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
       0.794
fni
Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
  
    0.771
ADI31247.1
PFAM: Radical SAM domain protein; KEGG: nam:NAMH_0848 radical SAM.
     0.730
Your Current Organism:
Staphylothermus hellenicus
NCBI taxonomy Id: 591019
Other names: S. hellenicus DSM 12710, Staphylothermus hellenicus BK20S6-10-b1, Staphylothermus hellenicus DSM 12710, Staphylothermus hellenicus P8, Staphylothermus hellenicus str. DSM 12710, Staphylothermus hellenicus strain DSM 12710, Staphylothermus sp. P8
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