| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADI32744.1 | eno | Shell_1659 | Shell_1177 | Conserved hypothetical protein. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.463 |
| ADI32744.1 | guaA | Shell_1659 | Shell_0033 | Conserved hypothetical protein. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.459 |
| ADI32744.1 | pan | Shell_1659 | Shell_1551 | Conserved hypothetical protein. | 26S proteasome subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...] | 0.433 |
| ADI32744.1 | rps7 | Shell_1659 | Shell_1658 | Conserved hypothetical protein. | Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. | 0.669 |
| eno | ADI32744.1 | Shell_1177 | Shell_1659 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Conserved hypothetical protein. | 0.463 |
| eno | guaA | Shell_1177 | Shell_0033 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.579 |
| eno | rps7 | Shell_1177 | Shell_1658 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. | 0.572 |
| guaA | ADI32744.1 | Shell_0033 | Shell_1659 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Conserved hypothetical protein. | 0.459 |
| guaA | eno | Shell_0033 | Shell_1177 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.579 |
| guaA | pan | Shell_0033 | Shell_1551 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 26S proteasome subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...] | 0.521 |
| guaA | rps7 | Shell_0033 | Shell_1658 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. | 0.796 |
| pan | ADI32744.1 | Shell_1551 | Shell_1659 | 26S proteasome subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...] | Conserved hypothetical protein. | 0.433 |
| pan | guaA | Shell_1551 | Shell_0033 | 26S proteasome subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...] | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.521 |
| rps7 | ADI32744.1 | Shell_1658 | Shell_1659 | Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. | Conserved hypothetical protein. | 0.669 |
| rps7 | eno | Shell_1658 | Shell_1177 | Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.572 |
| rps7 | guaA | Shell_1658 | Shell_0033 | Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.796 |