topA protein (Actinobacillus minor) - STRING interaction network

Nodes:

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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Textmining

[Homology]

Score

topA

DNA topoisomerase I. (866 aa)

Predicted Functional Partners:

EEV24606.1

0.999

leuS

0.999

EEV25214.1

0.955

EEV24599.1

0.908

recA

0.832

rpoA

0.823

ligA

0.784

rpoC

0.753

rnhA

0.737

EEV25209.1

0.718

Your Current Organism:

Actinobacillus minor

NCBI taxonomy Id: 591023
Other names: A. minor 202, Actinobacillus minor 202, Actinobacillus minor str. 202, Actinobacillus minor strain 202

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EEV24599.1	EEV24606.1	AM202_00195	AM202_00230	DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI).	COG0514 Superfamily II DNA helicase.	0.977
EEV24599.1	EEV25209.1	AM202_00195	AM202_03275	DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI).	Putative ATP-dependent helicase; COG1199 Rad3-related DNA helicases.	0.970
EEV24599.1	EEV25214.1	AM202_00195	AM202_03300	DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI).	COG0629 Single-stranded DNA-binding protein.	0.622
EEV24599.1	leuS	AM202_00195	AM202_06168	DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI).	COG0495 Leucyl-tRNA synthetase.	0.652
EEV24599.1	ligA	AM202_00195	AM202_0353	DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI).	DNA ligase.	0.663
EEV24599.1	recA	AM202_00195	AM202_0440	DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI).	Recombinase A.	0.999
EEV24599.1	rnhA	AM202_00195	AM202_0820	DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI).	Ribonuclease HI.	0.839
EEV24599.1	rpoC	AM202_00195	AM202_0412	DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI).	DNA-directed RNA polymerase subunit beta'.	0.410
EEV24599.1	topA	AM202_00195	AM202_0073	DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI).	DNA topoisomerase I.	0.908
EEV24606.1	EEV24599.1	AM202_00230	AM202_00195	COG0514 Superfamily II DNA helicase.	DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI).	0.977
EEV24606.1	EEV25209.1	AM202_00230	AM202_03275	COG0514 Superfamily II DNA helicase.	Putative ATP-dependent helicase; COG1199 Rad3-related DNA helicases.	0.711
EEV24606.1	EEV25214.1	AM202_00230	AM202_03300	COG0514 Superfamily II DNA helicase.	COG0629 Single-stranded DNA-binding protein.	0.602
EEV24606.1	recA	AM202_00230	AM202_0440	COG0514 Superfamily II DNA helicase.	Recombinase A.	0.942
EEV24606.1	rnhA	AM202_00230	AM202_0820	COG0514 Superfamily II DNA helicase.	Ribonuclease HI.	0.481
EEV24606.1	topA	AM202_00230	AM202_0073	COG0514 Superfamily II DNA helicase.	DNA topoisomerase I.	0.999
EEV25209.1	EEV24599.1	AM202_03275	AM202_00195	Putative ATP-dependent helicase; COG1199 Rad3-related DNA helicases.	DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI).	0.970
EEV25209.1	EEV24606.1	AM202_03275	AM202_00230	Putative ATP-dependent helicase; COG1199 Rad3-related DNA helicases.	COG0514 Superfamily II DNA helicase.	0.711
EEV25209.1	recA	AM202_03275	AM202_0440	Putative ATP-dependent helicase; COG1199 Rad3-related DNA helicases.	Recombinase A.	0.682
EEV25209.1	rpoA	AM202_03275	AM202_0619	Putative ATP-dependent helicase; COG1199 Rad3-related DNA helicases.	DNA-directed RNA polymerase subunit alpha.	0.997
EEV25209.1	rpoC	AM202_03275	AM202_0412	Putative ATP-dependent helicase; COG1199 Rad3-related DNA helicases.	DNA-directed RNA polymerase subunit beta'.	0.939