topB2 protein (Actinobacillus minor) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

topB2

DNA topoisomerase III. (633 aa)

Predicted Functional Partners:

EEV24606.1

0.990

recA

0.762

EEV24599.1

0.754

hepA

0.688

mepA

0.608

EEV25209.1

0.607

leuS

0.607

EEV25138.1

0.600

EEV24441.1

0.572

EEV25214.1

0.569

Your Current Organism:

Actinobacillus minor

NCBI taxonomy Id: 591023
Other names: A. minor 202, Actinobacillus minor 202, Actinobacillus minor str. 202, Actinobacillus minor strain 202

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EEV24441.1	EEV24599.1	AM202_05774	AM202_00195	single-stranded-DNA-specific exonuclease RecJ; COG0608 Single-stranded DNA-specific exonuclease.	DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI).	0.504
EEV24441.1	EEV24606.1	AM202_05774	AM202_00230	single-stranded-DNA-specific exonuclease RecJ; COG0608 Single-stranded DNA-specific exonuclease.	COG0514 Superfamily II DNA helicase.	0.563
EEV24441.1	EEV25214.1	AM202_05774	AM202_03300	single-stranded-DNA-specific exonuclease RecJ; COG0608 Single-stranded DNA-specific exonuclease.	COG0629 Single-stranded DNA-binding protein.	0.579
EEV24441.1	topB2	AM202_05774	AM202_104	single-stranded-DNA-specific exonuclease RecJ; COG0608 Single-stranded DNA-specific exonuclease.	DNA topoisomerase III.	0.572
EEV24599.1	EEV24441.1	AM202_00195	AM202_05774	DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI).	single-stranded-DNA-specific exonuclease RecJ; COG0608 Single-stranded DNA-specific exonuclease.	0.504
EEV24599.1	EEV24606.1	AM202_00195	AM202_00230	DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI).	COG0514 Superfamily II DNA helicase.	0.977
EEV24599.1	EEV25138.1	AM202_00195	AM202_02910	DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI).	DNA polymerase III subunit delta; COG0470 ATPase involved in DNA replication.	0.965
EEV24599.1	EEV25209.1	AM202_00195	AM202_03275	DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI).	Putative ATP-dependent helicase; COG1199 Rad3-related DNA helicases.	0.970
EEV24599.1	EEV25214.1	AM202_00195	AM202_03300	DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI).	COG0629 Single-stranded DNA-binding protein.	0.622
EEV24599.1	hepA	AM202_00195	AM202_0651	DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI).	ATP-dependent helicase HepA.	0.994
EEV24599.1	leuS	AM202_00195	AM202_06168	DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI).	COG0495 Leucyl-tRNA synthetase.	0.652
EEV24599.1	recA	AM202_00195	AM202_0440	DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI).	Recombinase A.	0.999
EEV24599.1	topB2	AM202_00195	AM202_104	DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI).	DNA topoisomerase III.	0.754
EEV24606.1	EEV24441.1	AM202_00230	AM202_05774	COG0514 Superfamily II DNA helicase.	single-stranded-DNA-specific exonuclease RecJ; COG0608 Single-stranded DNA-specific exonuclease.	0.563
EEV24606.1	EEV24599.1	AM202_00230	AM202_00195	COG0514 Superfamily II DNA helicase.	DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI).	0.977
EEV24606.1	EEV25138.1	AM202_00230	AM202_02910	COG0514 Superfamily II DNA helicase.	DNA polymerase III subunit delta; COG0470 ATPase involved in DNA replication.	0.841
EEV24606.1	EEV25209.1	AM202_00230	AM202_03275	COG0514 Superfamily II DNA helicase.	Putative ATP-dependent helicase; COG1199 Rad3-related DNA helicases.	0.711
EEV24606.1	EEV25214.1	AM202_00230	AM202_03300	COG0514 Superfamily II DNA helicase.	COG0629 Single-stranded DNA-binding protein.	0.602
EEV24606.1	hepA	AM202_00230	AM202_0651	COG0514 Superfamily II DNA helicase.	ATP-dependent helicase HepA.	0.855
EEV24606.1	recA	AM202_00230	AM202_0440	COG0514 Superfamily II DNA helicase.	Recombinase A.	0.942