EFK98108.1 protein (Streptomyces sp. SPB78) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

EFK98108.1

ATPase; Truncated CDS. (170 aa)

Predicted Functional Partners:

EFL01772.1

0.886

glpK

0.862

EFL02267.1

0.854

arc

0.833

rplJ

0.782

EFL00944.1

0.770

dnaK

0.761

EFL00812.1

0.754

EFK99495.1

0.737

EFK99024.1

0.731

Your Current Organism:

Streptomyces sp. SPB78

NCBI taxonomy Id: 591157
Other names: S. sp. SPB78

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EFK98108.1	EFK99024.1	SSLG_00166	SSLG_01083	ATPase; Truncated CDS.	Conserved hypothetical protein.	0.731
EFK98108.1	EFK99495.1	SSLG_00166	SSLG_01554	ATPase; Truncated CDS.	Conserved hypothetical protein.	0.737
EFK98108.1	EFL00812.1	SSLG_00166	SSLG_02870	ATPase; Truncated CDS.	WD-repeat protein.	0.754
EFK98108.1	EFL00944.1	SSLG_00166	SSLG_03002	ATPase; Truncated CDS.	Conserved hypothetical protein.	0.770
EFK98108.1	EFL01772.1	SSLG_00166	SSLG_03830	ATPase; Truncated CDS.	Acetoin dehydrogenase.	0.886
EFK98108.1	EFL02267.1	SSLG_00166	SSLG_04325	ATPase; Truncated CDS.	Mov34/MPN/PAD-1 family protein.	0.854
EFK98108.1	arc	SSLG_00166	SSLG_00885	ATPase; Truncated CDS.	AAA-family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.	0.833
EFK98108.1	dnaK	SSLG_00166	SSLG_03033	ATPase; Truncated CDS.	Chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.761
EFK98108.1	glpK	SSLG_00166	SSLG_00901	ATPase; Truncated CDS.	Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.	0.862
EFK98108.1	rplJ	SSLG_00166	SSLG_04075	ATPase; Truncated CDS.	50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.	0.782
EFK99024.1	EFK98108.1	SSLG_01083	SSLG_00166	Conserved hypothetical protein.	ATPase; Truncated CDS.	0.731
EFK99024.1	EFK99495.1	SSLG_01083	SSLG_01554	Conserved hypothetical protein.	Conserved hypothetical protein.	0.864
EFK99024.1	EFL00812.1	SSLG_01083	SSLG_02870	Conserved hypothetical protein.	WD-repeat protein.	0.494
EFK99024.1	EFL01772.1	SSLG_01083	SSLG_03830	Conserved hypothetical protein.	Acetoin dehydrogenase.	0.886
EFK99024.1	EFL02267.1	SSLG_01083	SSLG_04325	Conserved hypothetical protein.	Mov34/MPN/PAD-1 family protein.	0.667
EFK99024.1	arc	SSLG_01083	SSLG_00885	Conserved hypothetical protein.	AAA-family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.	0.406
EFK99024.1	dnaK	SSLG_01083	SSLG_03033	Conserved hypothetical protein.	Chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.737
EFK99024.1	glpK	SSLG_01083	SSLG_00901	Conserved hypothetical protein.	Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.	0.482
EFK99024.1	rplJ	SSLG_01083	SSLG_04075	Conserved hypothetical protein.	50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.	0.719
EFK99495.1	EFK98108.1	SSLG_01554	SSLG_00166	Conserved hypothetical protein.	ATPase; Truncated CDS.	0.737