Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EFK98467.1Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system. (99 aa)    
Predicted Functional Partners:
EFL00178.1
txe/YoeB family addiction module toxin.
  
 0.883
EFL00420.1
Conserved hypothetical protein.
 
 
 0.811
clpP
ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
       0.759
ureA
Urease, gamma subunit; Belongs to the urease gamma subunit family.
       0.729
EFK98469.1
Conserved hypothetical protein.
       0.723
ureC
Urease, alpha subunit.
       0.721
ureB
Urease, beta subunit; Belongs to the urease beta subunit family.
       0.721
EFK99015.1
Conserved hypothetical protein.
  
     0.676
ureF
Urease accessory protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
       0.661
EFK98462.1
Urease accessory protein UreG; Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
       0.655
Your Current Organism:
Streptomyces sp. SPB78
NCBI taxonomy Id: 591157
Other names: S. sp. SPB78
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