Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EFK98478.1G/U mismatch-specific DNA glycosylase. (184 aa)    
Predicted Functional Partners:
EFK98477.1
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
       0.819
EFK98476.1
Lipolytic enzyme.
       0.698
EFK98472.1
Acetyltransferase.
       0.593
EFK98972.1
3-methyladenine DNA glycosylase; Belongs to the DNA glycosylase MPG family.
      
 0.580
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
   
  
 0.546
cysS
cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
      
 0.528
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
    
  0.521
EFL00535.1
5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
     
  0.514
EFL00525.1
Exodeoxyribonuclease III.
    
 0.486
EFL03483.1
Exodeoxyribonuclease III.
    
 0.486
Your Current Organism:
Streptomyces sp. SPB78
NCBI taxonomy Id: 591157
Other names: S. sp. SPB78
Server load: low (14%) [HD]