Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFK98494.1Alkaline phosphatase. (434 aa)    
Predicted Functional Partners:
EFL01038.1
Alkaline phosphatase; Belongs to the alkaline phosphatase family.
  
 
 0.935
EFK99408.1
Alkaline phosphatase.
  
  
  0.916
folE
GTP cyclohydrolase I.
    
 0.862
EFL03158.1
Secreted alkaline phosphatase.
  
  
 
0.781
EFK98486.1
GntR family transcriptional regulator.
       0.530
EFK98499.1
Conserved hypothetical protein.
       0.530
EFL01485.1
Phosphate ABC transporter, phosphate-binding protein PstS; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.
      
 0.518
nadK
Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
  0.500
EFL02965.1
Two-component system sensor kinase.
 
   
 0.495
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
      
 0.464
Your Current Organism:
Streptomyces sp. SPB78
NCBI taxonomy Id: 591157
Other names: S. sp. SPB78
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