Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EFK98910.1GntR-family transcriptional regulator. (130 aa)    
Predicted Functional Partners:
EFL02582.1
GntR family transcriptional regulator.
  
   
 0.824
EFL02402.1
Transcriptional regulator.
   
    0.771
EFL02221.1
Conserved hypothetical protein; Belongs to the UPF0301 (AlgH) family.
   
    0.716
EFK99631.1
Metal uptake regulation protein; Belongs to the Fur family.
  
    0.645
EFL02984.1
Chromosome replication initiation inhibitor protein; Belongs to the LysR transcriptional regulatory family.
   
    0.631
EFK98908.1
Transcriptional regulator.
       0.551
EFK98909.1
Conserved hypothetical protein.
       0.551
cobB
Sir2 family regulator protein; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class II subfamily.
  
    0.551
EFK98913.1
Acetyltransferase.
       0.530
EFK98914.1
Conserved hypothetical protein.
       0.530
Your Current Organism:
Streptomyces sp. SPB78
NCBI taxonomy Id: 591157
Other names: S. sp. SPB78
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.