Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EFK99052.1Conserved hypothetical protein; Belongs to the LysR transcriptional regulatory family. (324 aa)    
Predicted Functional Partners:
EFK99051.1
Dihydrodipicolinate synthase; Belongs to the DapA family.
 
    0.828
EFL03389.1
Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.711
EFL00669.1
Regulatory protein; Belongs to the LysR transcriptional regulatory family.
  
     0.702
EFL00169.1
LysR-family transcriptional regulator; Truncated CDS; unextendable partial coding region.
  
     0.672
EFL01186.1
LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.661
EFL03799.1
lysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.641
EFL03425.1
HTH-type transcriptional regulator alsR; Belongs to the LysR transcriptional regulatory family.
  
     0.634
EFL02200.1
lysR-family transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.622
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.574
EFK99999.1
Hydrogen peroxide sensing regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.557
Your Current Organism:
Streptomyces sp. SPB78
NCBI taxonomy Id: 591157
Other names: S. sp. SPB78
Server load: low (16%) [HD]