Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EFK99344.1Glutamine synthetase, type I. (469 aa)    
Predicted Functional Partners:
EFK99171.1
Glutamate synthase(NADPH) large subunit.
  
 
 0.940
EFL00168.1
Glutamate dehydrogenase; Unextendable partial coding region; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.932
EFK99358.1
Glutamine synthetase.
     
 0.927
EFK99170.1
Glutamate synthase (NADPH), homotetrameric; Unextendable partial coding region.
  
 
 0.919
EFL02157.1
NAD-glutamate dehydrogenase.
     
 0.915
EFL03495.1
Gamma-glutamyltransferase.
     
 0.902
EFL00734.1
Glutamine synthetase; Truncated CDS; Belongs to the glutamine synthetase family.
  
  
0.898
carB
Carbamoyl-phosphate synthase, large subunit; Truncated CDS; Belongs to the CarB family.
 
 0.894
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
 
 0.883
EFK99375.1
Glutamine synthetase, type I.
 
  
 
0.882
Your Current Organism:
Streptomyces sp. SPB78
NCBI taxonomy Id: 591157
Other names: S. sp. SPB78
Server load: low (12%) [HD]