EFL00078.1 protein (Streptomyces sp. SPB78) - STRING interaction network

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[Homology]

Score

EFL00078.1

Histidine ammonia-lyase. (539 aa)

Predicted Functional Partners:

hutU

0.987

EFL00079.1

0.953

hutI

0.953

EFL00077.1

0.773

hisC

0.767

pat

0.767

aroC

0.750

EFL03562.1

0.749

EFK99030.1

0.748

trpE

0.745

Your Current Organism:

Streptomyces sp. SPB78

NCBI taxonomy Id: 591157
Other names: S. sp. SPB78

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EFK99030.1	EFL00078.1	SSLG_01089	SSLG_02136	Amidohydrolase 3.	Histidine ammonia-lyase.	0.748
EFK99030.1	hutU	SSLG_01089	SSLG_04119	Amidohydrolase 3.	Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.	0.920
EFL00077.1	EFL00078.1	SSLG_02135	SSLG_02136	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component.	Histidine ammonia-lyase.	0.773
EFL00077.1	EFL00079.1	SSLG_02135	SSLG_02137	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component.	Type II beta-Tyr adenylation domain-containing protein.	0.905
EFL00078.1	EFK99030.1	SSLG_02136	SSLG_01089	Histidine ammonia-lyase.	Amidohydrolase 3.	0.748
EFL00078.1	EFL00077.1	SSLG_02136	SSLG_02135	Histidine ammonia-lyase.	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component.	0.773
EFL00078.1	EFL00079.1	SSLG_02136	SSLG_02137	Histidine ammonia-lyase.	Type II beta-Tyr adenylation domain-containing protein.	0.953
EFL00078.1	EFL03562.1	SSLG_02136	SSLG_05620	Histidine ammonia-lyase.	Conserved hypothetical protein.	0.749
EFL00078.1	aroC	SSLG_02136	SSLG_00738	Histidine ammonia-lyase.	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	0.750
EFL00078.1	hisC	SSLG_02136	SSLG_01254	Histidine ammonia-lyase.	Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.767
EFL00078.1	hutI	SSLG_02136	SSLG_04122	Histidine ammonia-lyase.	Imidazolonepropionase.	0.953
EFL00078.1	hutU	SSLG_02136	SSLG_04119	Histidine ammonia-lyase.	Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.	0.987
EFL00078.1	pat	SSLG_02136	SSLG_03231	Histidine ammonia-lyase.	Histidinol-phosphate aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.	0.767
EFL00078.1	trpE	SSLG_02136	SSLG_01244	Histidine ammonia-lyase.	Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]	0.745
EFL00079.1	EFL00077.1	SSLG_02137	SSLG_02135	Type II beta-Tyr adenylation domain-containing protein.	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component.	0.905
EFL00079.1	EFL00078.1	SSLG_02137	SSLG_02136	Type II beta-Tyr adenylation domain-containing protein.	Histidine ammonia-lyase.	0.953
EFL00079.1	EFL03562.1	SSLG_02137	SSLG_05620	Type II beta-Tyr adenylation domain-containing protein.	Conserved hypothetical protein.	0.641
EFL00079.1	hisC	SSLG_02137	SSLG_01254	Type II beta-Tyr adenylation domain-containing protein.	Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.490
EFL00079.1	pat	SSLG_02137	SSLG_03231	Type II beta-Tyr adenylation domain-containing protein.	Histidinol-phosphate aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.	0.490
EFL00079.1	trpE	SSLG_02137	SSLG_01244	Type II beta-Tyr adenylation domain-containing protein.	Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]	0.816