Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL00143.1Dihydrolipoyl dehydrogenase. (476 aa)    
Predicted Functional Partners:
EFL02609.1
Oxoglutarate dehydrogenase (succinyl-transferring), E1 component.
 
 0.997
EFL01270.1
Branched-chain alpha keto acid dehydrogenase E1 beta subunit.
 
 0.988
EFK99328.1
2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase.
 0.979
EFL01261.1
Branched-chain alpha-keto acid dehydrogenase subunit E2.
 
 0.974
EFL01271.1
Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase.
 0.974
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
 
 0.949
EFL01269.1
Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit.
 
 
 0.940
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 
 0.896
gcvT
Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.
 
 0.883
EFK99330.1
Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.879
Your Current Organism:
Streptomyces sp. SPB78
NCBI taxonomy Id: 591157
Other names: S. sp. SPB78
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