Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
EFL00395.1Cystathionine beta-synthase. (462 aa)    
Predicted Functional Partners:
EFL00124.1
Methionine gamma-lyase.
 
 0.996
EFL01185.1
Methionine gamma-lyase.
 
 0.991
EFL00802.1
O-succinylhomoserine sulfhydrylase.
 
 
 0.935
EFK98837.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.924
EFL01386.1
Adenosylhomocysteinase.
 
 0.902
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
 
 0.902
EFK98986.1
Phosphoserine phosphatase.
    
 0.895
EFL02639.1
Homoserine dehydrogenase.
 
 
 0.889
EFL04187.1
Cysteine synthase/cystathionine beta-synthase.
  
  
  0.886
metXA
Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
    
 0.884
Your Current Organism:
Streptomyces sp. SPB78
NCBI taxonomy Id: 591157
Other names: S. sp. SPB78
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