Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EFL00410.1Transcriptional regulator. (221 aa)    
Predicted Functional Partners:
EFL00411.1
Light-dependent protochlorophyllide reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
     0.735
cobB
Sir2 family regulator protein; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class II subfamily.
   
    0.645
EFL02694.1
MarR-transcriptional regulator.
   
    0.598
EFL00412.1
Predicted protein.
       0.545
EFL02984.1
Chromosome replication initiation inhibitor protein; Belongs to the LysR transcriptional regulatory family.
   
   0.520
EFL01015.1
Conserved hypothetical protein.
  
     0.517
EFK99083.1
DNA-binding protein.
   
    0.496
EFL02092.1
Transcriptional regulator.
   
    0.494
EFL02094.1
Transcriptional regulator.
   
    0.494
EFK99223.1
Conserved hypothetical protein.
  
     0.453
Your Current Organism:
Streptomyces sp. SPB78
NCBI taxonomy Id: 591157
Other names: S. sp. SPB78
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