Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EFL00539.1Major facilitator superfamily transporter permease. (457 aa)    
Predicted Functional Partners:
EFL00540.1
FmdB family regulatory protein.
       0.767
EFL00538.1
Potassium/proton antiporter.
       0.717
EFL00536.1
Penicillin acylase.
       0.629
EFL00541.1
Methylthioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage.
       0.530
mscL
Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
  
    0.528
EFK98837.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 
  0.454
EFK98685.1
Secreted protein.
  
     0.424
EFK98714.1
DNA polymerase III subunit epsilon.
  
     0.413
EFL02499.1
ABC transporter solute-binding protein.
  
     0.411
Your Current Organism:
Streptomyces sp. SPB78
NCBI taxonomy Id: 591157
Other names: S. sp. SPB78
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