Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL01269.1Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit. (420 aa)    
Predicted Functional Partners:
EFL01270.1
Branched-chain alpha keto acid dehydrogenase E1 beta subunit.
 0.999
EFL01271.1
Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase.
 
 0.996
EFL01261.1
Branched-chain alpha-keto acid dehydrogenase subunit E2.
 
 0.989
EFK99327.1
Dihydrolipoyl dehydrogenase.
 
 
 0.987
EFK99328.1
2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase.
 
 0.985
EFL02609.1
Oxoglutarate dehydrogenase (succinyl-transferring), E1 component.
 
 0.984
EFL00143.1
Dihydrolipoyl dehydrogenase.
 
 
 0.940
EFL01430.1
Valine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.930
EFL03940.1
Dihydrolipoyl dehydrogenase.
 
 
 0.896
EFL01956.1
Oxidoreductase.
    
 0.889
Your Current Organism:
Streptomyces sp. SPB78
NCBI taxonomy Id: 591157
Other names: S. sp. SPB78
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