Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EFL01373.1Conserved hypothetical protein. (257 aa)    
Predicted Functional Partners:
EFL01375.1
ATP-binding protein.
  
    0.801
EFL01374.1
Conserved hypothetical protein.
       0.775
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 0.729
EFL02301.1
DNA-cytosine methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
  
  
  0.726
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
  0.697
EFL02300.1
DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
  
  
  0.673
EFL03394.1
Imidazolonepropionase.
   
 
  0.626
EFL01110.1
DNA cytocine methyl transferase.
     
  0.546
EFL01645.1
Phage DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
 
    
0.426
EFK99916.1
Tripeptidyl aminopeptidase; Unextendable partial coding region.
  
     0.416
Your Current Organism:
Streptomyces sp. SPB78
NCBI taxonomy Id: 591157
Other names: S. sp. SPB78
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