Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EFL01424.1Conserved hypothetical protein. (156 aa)    
Predicted Functional Partners:
EFL01422.1
TetR-family transcriptional regulator.
       0.721
EFL01423.1
Kanamycin acetyltransferase.
       0.634
EFK98276.1
Beta-ketoadipyl CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
   
   0.597
EFK99452.1
Predicted protein.
   
   0.597
EFL00397.1
Beta-ketoadipyl CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
   
   0.597
EFL02682.1
Beta-ketoadipyl CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
   
   0.597
EFL03238.1
Beta-ketoadipyl CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
   
   0.597
EFL03639.1
Beta-ketoadipyl CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
   
   0.597
EFL01417.1
Conserved hypothetical protein.
       0.530
purS
Phosphoribosylformylglycinamidine synthase, purS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...]
       0.530
Your Current Organism:
Streptomyces sp. SPB78
NCBI taxonomy Id: 591157
Other names: S. sp. SPB78
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