Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL01430.1Valine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (379 aa)    
Predicted Functional Partners:
EFK99171.1
Glutamate synthase(NADPH) large subunit.
  
 0.986
EFL01269.1
Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit.
  
 
 0.930
EFL02609.1
Oxoglutarate dehydrogenase (succinyl-transferring), E1 component.
  
 0.917
EFL01270.1
Branched-chain alpha keto acid dehydrogenase E1 beta subunit.
 
 
 0.914
EFL01956.1
Oxidoreductase.
  
 
 0.877
EFL02802.1
Branched-chain amino acid aminotransferase.
  
 
 0.874
EFL04024.1
Branched-chain amino acid aminotransferase.
  
 
 0.873
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
 
 0.848
EFL03248.1
Glutamate synthase(ferredoxin); Belongs to the glutamate synthase family.
  
 0.796
EFL02454.1
Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
    
 0.758
Your Current Organism:
Streptomyces sp. SPB78
NCBI taxonomy Id: 591157
Other names: S. sp. SPB78
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