Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL01951.1Haloacid dehalogenase, type II. (244 aa)    
Predicted Functional Partners:
EFL01426.1
Hydrolase.
  
 
  0.896
EFL00150.1
Betaine aldehyde dehydrogenase.
     
  0.848
EFL01952.1
Integral membrane protein.
       0.737
EFL01706.1
2-hydroxymuconic semialdehyde dehydrogenase.
     
  0.697
EFL03939.1
Benzaldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
     
  0.697
EFK98634.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
    
 0.654
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.635
EFK98044.1
Betaine aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
     
  0.607
EFL00017.1
Betaine aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
     
  0.607
guaA
GMP synthase domain-containing protein; Catalyzes the synthesis of GMP from XMP.
    
  0.607
Your Current Organism:
Streptomyces sp. SPB78
NCBI taxonomy Id: 591157
Other names: S. sp. SPB78
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