Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EFL02356.1Secreted protein; Overlaps another CDS with the same product name. (195 aa)    
Predicted Functional Partners:
EFL02357.1
Secreted protein; Overlaps another CDS with the same product name.
       0.888
EFL02355.1
Conserved hypothetical protein.
       0.824
EFL00513.1
Conserved hypothetical protein.
   
 0.780
EFL02354.1
Predicted protein.
       0.765
EFL01408.1
Integral membrane protein.
     
 0.715
guaA
GMP synthase domain-containing protein; Catalyzes the synthesis of GMP from XMP.
  
 
  0.702
EFL02352.1
Predicted protein.
       0.695
EFL02353.1
Two-component system response regulator.
       0.695
EFL02965.1
Two-component system sensor kinase.
  
 
 0.686
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.677
Your Current Organism:
Streptomyces sp. SPB78
NCBI taxonomy Id: 591157
Other names: S. sp. SPB78
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