Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EFL02441.1Nickel import ATP-binding protein NikE; Belongs to the ABC transporter superfamily. (375 aa)    
Predicted Functional Partners:
EFL02439.1
Nickel ABC transporter, permease subunit NikC.
  0.981
EFL02438.1
Nickel ABC transporter, permease subunit NikB.
 
  0.975
EFK98284.1
Peptide/opine/nickel uptake family ABC transporter.
 
0.963
EFL02434.1
Nickel ABC transporter, permease subunit NikC.
  0.950
EFL02440.1
D-methionine ABC transporter, ATP-binding protein; Belongs to the ABC transporter superfamily.
 
 
0.948
EFL03730.1
Nickel ABC transporter, permease subunit NikB.
 
  0.937
EFL02433.1
Nickel ABC transporter, permease subunit NikB.
 
  0.926
EFL03955.1
Nickel ABC transporter, permease subunit NikC.
 0.924
EFL03731.1
Nickel ABC transporter, permease subunit NikC.
 
  0.917
EFL02753.1
Nickel ABC transporter, permease subunit NikC.
 0.899
Your Current Organism:
Streptomyces sp. SPB78
NCBI taxonomy Id: 591157
Other names: S. sp. SPB78
Server load: low (6%) [HD]