Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EFL02456.1Conserved hypothetical protein. (346 aa)    
Predicted Functional Partners:
EFL02457.1
Succinyl-diaminopimelate desuccinylase.
 
     0.817
EFL02458.1
Lysine decarboxylase; Belongs to the LOG family.
 
 
  0.749
EFL01740.1
Lsr2.
  
     0.658
guaA
GMP synthase domain-containing protein; Catalyzes the synthesis of GMP from XMP.
    
 0.648
tmk-2
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
 
  0.584
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.582
EFL01417.1
Conserved hypothetical protein.
  
     0.582
EFL00265.1
Cytidine deaminase.
    
  0.566
EFK98651.1
Inosine-5'-monophosphate dehydrogenase; Unextendable partial coding region.
     
  0.551
EFL02773.1
Methionine synthase.
  
     0.549
Your Current Organism:
Streptomyces sp. SPB78
NCBI taxonomy Id: 591157
Other names: S. sp. SPB78
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.