Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL02612.1Spermidine synthase. (236 aa)    
Predicted Functional Partners:
EFL02611.1
Phosphate regulon transcriptional regulatory protein PhoB.
       0.751
EFL02610.1
Two-component system sensor kinase.
       0.698
EFL02609.1
Oxoglutarate dehydrogenase (succinyl-transferring), E1 component.
  
  
 0.637
EFL00936.1
Spermidine synthase.
 
  
  0.550
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 
 0.531
EFL02599.1
Conserved hypothetical protein.
       0.530
lon
ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
       0.530
EFL03133.1
Amino acid decarboxylase.
  
 
 0.524
EFK99950.1
Formimidoylglutamase; Belongs to the arginase family.
  
 
 0.507
EFL03554.1
Arginase; Belongs to the arginase family.
  
 
 0.507
Your Current Organism:
Streptomyces sp. SPB78
NCBI taxonomy Id: 591157
Other names: S. sp. SPB78
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