Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL02711.1Alpha-1,2-mannosidase. (1027 aa)    
Predicted Functional Partners:
EFK99301.1
Cytochrome C heme-binding subunit.
  
 0.805
EFK99171.1
Glutamate synthase(NADPH) large subunit.
    
  0.791
EFL00079.1
Type II beta-Tyr adenylation domain-containing protein.
  
 
  0.722
EFK98837.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.717
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.674
guaA
GMP synthase domain-containing protein; Catalyzes the synthesis of GMP from XMP.
    
  0.665
EFL02223.1
Sugar hydrolase.
 
   
 0.625
EFK99141.1
Beta-hexosaminidase.
 
   
 0.613
EFL00822.1
Amino acid adenylation; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
  0.590
EFK99565.1
Non-ribosomal peptide synthetase.
  
 
  0.563
Your Current Organism:
Streptomyces sp. SPB78
NCBI taxonomy Id: 591157
Other names: S. sp. SPB78
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