Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL02726.1ABC transporter. (1244 aa)    
Predicted Functional Partners:
EFK98798.1
Glycine betaine ABC transport system permease.
     
  0.817
EFL01170.1
ABC transporter ATP-binding protein.
  
 
  0.808
dnaK
Chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
  0.760
EFK98985.1
ABC transporter ATP-binding protein.
   
 0.718
EFL03762.1
Beta keto-acyl synthase; Truncated CDS; unextendable partial coding region.
   
 0.707
EFL00079.1
Type II beta-Tyr adenylation domain-containing protein.
  
 0.704
EFK99586.1
Lipid A export permease/ATP-binding protein MsbA; Overlaps another CDS with the same product name.
 
  
 
0.602
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
 
  0.594
EFL02678.1
ABC transporter integral membrane subunit.
  
 
  0.589
EFL00825.1
ABC transporter ATP-binding protein; Belongs to the ABC transporter superfamily.
     
  0.572
Your Current Organism:
Streptomyces sp. SPB78
NCBI taxonomy Id: 591157
Other names: S. sp. SPB78
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