Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL03071.1Turgor pressure sensor protein. (1111 aa)    
Predicted Functional Partners:
EFL02965.1
Two-component system sensor kinase.
  
 0.990
kdpC
K+-transporting ATPase, C subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
 
  
 0.965
kdpB
K+-transporting ATPase, B subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
 
  
 0.945
kdpA
K+-transporting ATPase, A subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.
 
  
 0.939
EFL03072.1
Nucleic acid binding protein.
       0.793
EFL03073.1
K+ transport system.
       0.793
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
       0.650
EFL03068.1
Conserved hypothetical protein.
       0.650
EFL03066.1
Secreted protein.
       0.622
EFL01120.1
Diguanylate cyclase; Unextendable partial coding region.
   
 0.586
Your Current Organism:
Streptomyces sp. SPB78
NCBI taxonomy Id: 591157
Other names: S. sp. SPB78
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