STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFL29739.1Metallophosphoesterase. (501 aa)    
Predicted Functional Partners:
EFL30644.1
Exonuclease; Overlaps another CDS with the same product name.
  
 0.998
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.996
EFL34711.1
ATP-dependent DNA helicase PcrA.
  
 0.987
EFL30983.1
5'-3' exonuclease.
   
 0.961
EFL35317.1
ATP-dependent helicase.
   
 0.951
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.942
EFL34151.1
ATP-dependent DNA helicase RecQ.
   
 0.900
EFL35330.1
ATP-dependent DNA helicase.
   
 0.900
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 0.895
EFL31715.1
Conserved hypothetical protein.
  
 
  0.878
Your Current Organism:
Streptomyces viridochromogenes
NCBI taxonomy Id: 591159
Other names: S. viridochromogenes DSM 40736, Streptomyces viridochromogenes DSM 40736, Streptomyces viridochromogenes str. DSM 40736, Streptomyces viridochromogenes strain DSM 40736
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.