STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sfla_1617Terpene synthase metal-binding domain-containing protein; Catalyzes the conversion of (2E,6E)-farnesyl diphosphate (FPP) to yield the sesquiterpene (+)-(1(10)E,4E,6S,7R)-germacradien-6- ol via a putative 1,10-cyclization, which could require the abstraction of the pyrophosphate from FPP to yield the (E,E)-germacradienyl cation. The only accepted substrate is farnesyl diphosphate (FPP). (356 aa)    
Predicted Functional Partners:
Sfla_2037
Putative transcriptional regulator, Crp/Fnr family; KEGG: sgr:SGR_2264 putative nucleotide-binding protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding.
  
  
  0.754
Sfla_5668
KEGG: sgr:SGR_1270 putative nucleotide-binding protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding.
  
  
  0.754
Sfla_5667
PFAM: Terpene synthase metal-binding domain-containing protein; KEGG: sgr:SGR_1269 hypothetical protein.
  
   
 0.633
Sfla_2597
PFAM: monooxygenase FAD-binding; KEGG: sgr:SGR_2934 hypothetical protein.
  
     0.514
Sfla_5703
KEGG: sma:SAV_7492 ABC transporter ATP-binding protein; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase.
    
  0.440
Sfla_5704
KEGG: sma:SAV_7493 ABC transporter ATP-binding protein; PFAM: ABC transporter related; peptidase C39 bacteriocin processing; ABC transporter transmembrane region; SMART: AAA ATPase.
    
  0.440
Sfla_0768
KEGG: scb:SCAB_25591 putative cellulase.
  
     0.435
Sfla_1445
Ricin B lectin; KEGG: sgr:SGR_6347 hypothetical protein; PFAM: Ricin B lectin; SMART: Ricin B lectin.
  
     0.426
Sfla_2007
Lysozyme; PFAM: glycoside hydrolase family 25; KEGG: sgr:SGR_2220 putative secreted hydrolase; SMART: Glycoside hydrolase, family 25 subgroup.
  
     0.408
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.402
Your Current Organism:
Streptomyces pratensis
NCBI taxonomy Id: 591167
Other names: S. pratensis ATCC 33331, Streptomyces flavogriseus ATCC 33331, Streptomyces pratensis ATCC 33331
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