STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sfla_1884Two component transcriptional regulator, LuxR family; KEGG: scb:SCAB_27841 putative two-component system response regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR. (218 aa)    
Predicted Functional Partners:
Sfla_1885
Integral membrane sensor signal transduction histidine kinase; KEGG: sco:SCO5454 two-component system sensor kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein.
 
 0.955
Sfla_1602
GAF sensor hybrid histidine kinase; KEGG: sgr:SGR_1773 putative two-component system sensor kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; histidine kinase HAMP region domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; histidine kinase HAMP region domain protein; response regulator receiver.
  
 
 0.849
Sfla_1032
Integral membrane sensor signal transduction histidine kinase; KEGG: sgr:SGR_1293 putative two-component system sensor kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein.
 
 0.830
Sfla_2810
Integral membrane sensor signal transduction histidine kinase; KEGG: sgr:SGR_4043 putative two-component system sensor kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein.
 
 
 0.817
Sfla_4658
Integral membrane sensor signal transduction histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: sgr:SGR_5343 putative two-component system sensor kinase.
 
 0.802
Sfla_2262
Integral membrane sensor signal transduction histidine kinase; KEGG: sgr:SGR_2524 putative two-component system sensor kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein.
 
 
 0.799
Sfla_0945
Integral membrane sensor signal transduction histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: sco:SCO6421 two-component system sensor kinase.
 
 
 0.795
Sfla_3480
Integral membrane sensor signal transduction histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: sgr:SGR_4104 putative two-component system sensor kinase.
 
 0.794
Sfla_5014
KEGG: sgr:SGR_5694 putative two-component system sensor kinase; PFAM: GAF domain protein; histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: GAF domain protein; ATP-binding region ATPase domain protein.
 
 0.794
Sfla_4448
Integral membrane sensor signal transduction histidine kinase; KEGG: sgr:SGR_5124 putative two-component system sensor kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein.
 
 
 0.782
Your Current Organism:
Streptomyces pratensis
NCBI taxonomy Id: 591167
Other names: S. pratensis ATCC 33331, Streptomyces flavogriseus ATCC 33331, Streptomyces pratensis ATCC 33331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.