STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sfla_2680PFAM: regulatory protein TetR; KEGG: sgr:SGR_3089 TetR family transcriptional regulator. (192 aa)    
Predicted Functional Partners:
Sfla_2686
PFAM: protein of unknown function DUF1446; KEGG: sgr:SGR_3095 hypothetical protein.
 
     0.922
Sfla_2687
KEGG: sgr:SGR_3096 hypothetical protein.
 
     0.906
Sfla_2683
PFAM: acyl-CoA dehydrogenase domain-containing protein; KEGG: sgr:SGR_3092 putative acyl-CoA dehydrogenase.
 
     0.878
Sfla_2681
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: sgr:SGR_3090 enoyl-CoA hydratase.
  
    0.865
Sfla_2682
PFAM: AMP-dependent synthetase and ligase; KEGG: sgr:SGR_3091 putative 4-coumarate:CoA ligase.
       0.865
Sfla_2685
KEGG: sgr:SGR_3094 putative acetyl/propionyl CoA carboxylase beta subunit; PFAM: carboxyl transferase.
 
     0.814
Sfla_2684
KEGG: sgr:SGR_3093 putative acetyl/propionyl CoA carboxylase alpha subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; Carbamoyl-phosphate synthetase large chain domain protein; biotin/lipoyl attachment domain-containing protein; SMART: biotin carboxylase domain protein.
 
 
   0.682
Sfla_0683
KEGG: sgr:SGR_997 hypothetical protein; PFAM: Saccharopine dehydrogenase.
  
     0.559
Sfla_4109
PFAM: periplasmic binding protein; KEGG: scb:SCAB_57981 putative protein DesF.
  
     0.456
Sfla_3716
Regulatory protein MerR; KEGG: sgr:SGR_4311 MerR family transcriptional regulator; PFAM: regulatory protein MerR; SMART: regulatory protein MerR.
  
     0.455
Your Current Organism:
Streptomyces pratensis
NCBI taxonomy Id: 591167
Other names: S. pratensis ATCC 33331, Streptomyces flavogriseus ATCC 33331, Streptomyces pratensis ATCC 33331
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.