Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Sfla_3203PFAM: cell cycle protein; KEGG: sgr:SGR_3727 FtsW/RodA/SpoVE family cell cycle protein; Belongs to the SEDS family. (466 aa)    
Predicted Functional Partners:
Sfla_3202
PFAM: penicillin-binding protein transpeptidase; KEGG: sgr:SGR_3726 penicillin-binding protein.
 
 0.989
Sfla_1988
Peptidoglycan glycosyltransferase; KEGG: sgr:SGR_2203 putative penicillin-binding protein; PFAM: penicillin-binding protein transpeptidase.
 
 0.962
Sfla_4938
PFAM: penicillin-binding protein transpeptidase; KEGG: sgr:SGR_5621 putative penicillin-binding protein.
 
 0.955
Sfla_3620
PFAM: penicillin-binding protein transpeptidase; KEGG: sgr:SGR_4232 putative penicillin-binding protein.
 
 0.934
ftsQ
Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily.
 
 
 0.934
Sfla_4730
KEGG: sgr:SGR_5415 putative peptidoglycan synthetase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain.
 
 
 0.895
Sfla_3204
KEGG: sgr:SGR_3728 putative protein phosphatase; PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein.
 
  
 0.886
Sfla_3206
FHA domain containing protein; KEGG: sgr:SGR_3730 hypothetical protein; PFAM: Protein of unknown function DUF2662; Forkhead-associated protein; SMART: Forkhead-associated protein.
 
   
 0.874
Sfla_3205
FHA domain containing protein; KEGG: sgr:SGR_3729 hypothetical protein; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein.
 
   
 0.863
murC
UDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
  
 0.817
Your Current Organism:
Streptomyces pratensis
NCBI taxonomy Id: 591167
Other names: S. pratensis ATCC 33331, Streptomyces flavogriseus ATCC 33331, Streptomyces pratensis ATCC 33331
Server load: low (26%) [HD]