STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sfla_5105PFAM: Methyltransferase type 11; NUDIX hydrolase; KEGG: sgr:SGR_5778 hypothetical protein. (492 aa)    
Predicted Functional Partners:
Sfla_5103
KEGG: sco:SCO1139 integral membrane protein.
 
     0.704
Sfla_5102
KEGG: sgr:SGR_5775 putative secreted protein.
 
     0.700
Sfla_4002
PFAM: small multidrug resistance protein; KEGG: sco:SCO2898 molecular chaperone.
      
 0.663
Sfla_5104
PFAM: protein of unknown function DUF112 transmembrane; KEGG: sgr:SGR_5777 putative integral membrane protein.
       0.658
Sfla_5099
KEGG: sgr:SGR_5773 putative cellulose-binding protein; TIGRFAM: LPXTG-motif cell wall anchor domain protein; PFAM: chitin-binding domain 3 protein.
       0.605
Sfla_5101
Response regulator receiver and unknown domain protein; KEGG: sgr:SGR_5774 putative two-component system response regulator; PFAM: response regulator receiver; SMART: response regulator receiver.
 
     0.575
Sfla_4173
PFAM: Methyltransferase type 11; KEGG: sgr:SGR_4831 putative methyltransferase.
  
  0.489
Sfla_0099
PFAM: phosphopantetheine-binding; KEGG: fal:FRAAL2557 non-ribosomal peptide synthetase (fragment).
     
 0.443
Sfla_4525
Phosphoglycerate mutase; KEGG: sgr:SGR_5214 bifunctional RNase H/acid phosphatase; PFAM: Phosphoglycerate mutase; ribonuclease H; SMART: Phosphoglycerate mutase.
 
    0.424
Sfla_6249
PFAM: Methyltransferase type 11; KEGG: fre:Franean1_4949 methyltransferase type 11.
  
  0.422
Your Current Organism:
Streptomyces pratensis
NCBI taxonomy Id: 591167
Other names: S. pratensis ATCC 33331, Streptomyces flavogriseus ATCC 33331, Streptomyces pratensis ATCC 33331
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