node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDD31131.1 | SDD37665.1 | SAMN05421538_101339 | SAMN05421538_101489 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glutamate synthase (NADPH/NADH) large chain. | 0.565 |
SDD31131.1 | SDE18462.1 | SAMN05421538_101339 | SAMN05421538_104255 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | CBS domain-containing protein. | 0.730 |
SDD31131.1 | guaA | SAMN05421538_101339 | SAMN05421538_10483 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.612 |
SDD31131.1 | purH | SAMN05421538_101339 | SAMN05421538_10343 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. | 0.923 |
SDD31131.1 | rpsF | SAMN05421538_101339 | SAMN05421538_101308 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Small subunit ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 0.839 |
SDD37665.1 | SDD31131.1 | SAMN05421538_101489 | SAMN05421538_101339 | Glutamate synthase (NADPH/NADH) large chain. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.565 |
SDD37665.1 | SDD41095.1 | SAMN05421538_101489 | SAMN05421538_101557 | Glutamate synthase (NADPH/NADH) large chain. | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.935 |
SDD37665.1 | SDE18462.1 | SAMN05421538_101489 | SAMN05421538_104255 | Glutamate synthase (NADPH/NADH) large chain. | CBS domain-containing protein. | 0.715 |
SDD37665.1 | SDE18494.1 | SAMN05421538_101489 | SAMN05421538_104256 | Glutamate synthase (NADPH/NADH) large chain. | DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family. | 0.556 |
SDD37665.1 | guaA | SAMN05421538_101489 | SAMN05421538_10483 | Glutamate synthase (NADPH/NADH) large chain. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.930 |
SDD37665.1 | guaB | SAMN05421538_101489 | SAMN05421538_104228 | Glutamate synthase (NADPH/NADH) large chain. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.980 |
SDD37665.1 | purA | SAMN05421538_101489 | SAMN05421538_10272 | Glutamate synthase (NADPH/NADH) large chain. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.640 |
SDD37665.1 | purH | SAMN05421538_101489 | SAMN05421538_10343 | Glutamate synthase (NADPH/NADH) large chain. | Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. | 0.947 |
SDD37665.1 | rpsF | SAMN05421538_101489 | SAMN05421538_101308 | Glutamate synthase (NADPH/NADH) large chain. | Small subunit ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 0.416 |
SDD41095.1 | SDD37665.1 | SAMN05421538_101557 | SAMN05421538_101489 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | Glutamate synthase (NADPH/NADH) large chain. | 0.935 |
SDD41095.1 | SDE18462.1 | SAMN05421538_101557 | SAMN05421538_104255 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | CBS domain-containing protein. | 0.690 |
SDD41095.1 | guaA | SAMN05421538_101557 | SAMN05421538_10483 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.854 |
SDD41095.1 | guaB | SAMN05421538_101557 | SAMN05421538_104228 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.716 |
SDE18462.1 | SDD31131.1 | SAMN05421538_104255 | SAMN05421538_101339 | CBS domain-containing protein. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.730 |
SDE18462.1 | SDD37665.1 | SAMN05421538_104255 | SAMN05421538_101489 | CBS domain-containing protein. | Glutamate synthase (NADPH/NADH) large chain. | 0.715 |