node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDD82169.1 | SDE27425.1 | SAMN05421538_102514 | SAMN05421538_105123 | Molecular chaperone IbpA; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | 0.751 |
SDD82169.1 | SDE64433.1 | SAMN05421538_102514 | SAMN05421538_10914 | Molecular chaperone IbpA; Belongs to the small heat shock protein (HSP20) family. | DnaJ domain-containing protein. | 0.453 |
SDD82169.1 | dnaJ | SAMN05421538_102514 | SAMN05421538_103155 | Molecular chaperone IbpA; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.566 |
SDD82169.1 | dnaK | SAMN05421538_102514 | SAMN05421538_103156 | Molecular chaperone IbpA; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.697 |
SDD82169.1 | grpE | SAMN05421538_102514 | SAMN05421538_101674 | Molecular chaperone IbpA; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.611 |
SDE15937.1 | SDE27425.1 | SAMN05421538_104190 | SAMN05421538_105123 | Molecular chaperone IbpA, HSP20 family; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | 0.736 |
SDE15937.1 | SDE64433.1 | SAMN05421538_104190 | SAMN05421538_10914 | Molecular chaperone IbpA, HSP20 family; Belongs to the small heat shock protein (HSP20) family. | DnaJ domain-containing protein. | 0.405 |
SDE15937.1 | dnaJ | SAMN05421538_104190 | SAMN05421538_103155 | Molecular chaperone IbpA, HSP20 family; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.405 |
SDE15937.1 | dnaK | SAMN05421538_104190 | SAMN05421538_103156 | Molecular chaperone IbpA, HSP20 family; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.630 |
SDE15937.1 | grpE | SAMN05421538_104190 | SAMN05421538_101674 | Molecular chaperone IbpA, HSP20 family; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.527 |
SDE27425.1 | SDD82169.1 | SAMN05421538_105123 | SAMN05421538_102514 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Molecular chaperone IbpA; Belongs to the small heat shock protein (HSP20) family. | 0.751 |
SDE27425.1 | SDE15937.1 | SAMN05421538_105123 | SAMN05421538_104190 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Molecular chaperone IbpA, HSP20 family; Belongs to the small heat shock protein (HSP20) family. | 0.736 |
SDE27425.1 | SDE47855.1 | SAMN05421538_105123 | SAMN05421538_10722 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Type VI secretion system protein ImpC. | 0.796 |
SDE27425.1 | SDE64433.1 | SAMN05421538_105123 | SAMN05421538_10914 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | DnaJ domain-containing protein. | 0.705 |
SDE27425.1 | clpP | SAMN05421538_105123 | SAMN05421538_101675 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease, protease subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.907 |
SDE27425.1 | clpP-2 | SAMN05421538_105123 | SAMN05421538_102546 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease, protease subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.907 |
SDE27425.1 | clpS | SAMN05421538_105123 | SAMN05421538_107123 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.964 |
SDE27425.1 | dnaJ | SAMN05421538_105123 | SAMN05421538_103155 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.707 |
SDE27425.1 | dnaK | SAMN05421538_105123 | SAMN05421538_103156 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.973 |
SDE27425.1 | grpE | SAMN05421538_105123 | SAMN05421538_101674 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.789 |