node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDD31131.1 | SDD42911.1 | SAMN05421538_101339 | SAMN05421538_101593 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.429 |
SDD31131.1 | SDE64744.1 | SAMN05421538_101339 | SAMN05421538_10921 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Hypothetical protein. | 0.429 |
SDD31131.1 | SDE84105.1 | SAMN05421538_101339 | SAMN05421538_11284 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glutaredoxin. | 0.603 |
SDD31131.1 | msrA | SAMN05421538_101339 | SAMN05421538_1094 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.528 |
SDD42911.1 | SDD31131.1 | SAMN05421538_101593 | SAMN05421538_101339 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.429 |
SDD42911.1 | SDE84105.1 | SAMN05421538_101593 | SAMN05421538_11284 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Glutaredoxin. | 0.863 |
SDD42911.1 | nrdI | SAMN05421538_101593 | SAMN05421538_101592 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Protein involved in ribonucleotide reduction; Probably involved in ribonucleotide reductase function. | 0.991 |
SDD42911.1 | ribA | SAMN05421538_101593 | SAMN05421538_10399 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.655 |
SDD42911.1 | ribB | SAMN05421538_101593 | SAMN05421538_102375 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.655 |
SDD65447.1 | SDE84105.1 | SAMN05421538_102140 | SAMN05421538_11284 | Sulfide:quinone oxidoreductase. | Glutaredoxin. | 0.606 |
SDE64744.1 | SDD31131.1 | SAMN05421538_10921 | SAMN05421538_101339 | Hypothetical protein. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.429 |
SDE64744.1 | SDE84105.1 | SAMN05421538_10921 | SAMN05421538_11284 | Hypothetical protein. | Glutaredoxin. | 0.863 |
SDE64744.1 | nrdI | SAMN05421538_10921 | SAMN05421538_101592 | Hypothetical protein. | Protein involved in ribonucleotide reduction; Probably involved in ribonucleotide reductase function. | 0.797 |
SDE64744.1 | ribA | SAMN05421538_10921 | SAMN05421538_10399 | Hypothetical protein. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.655 |
SDE64744.1 | ribB | SAMN05421538_10921 | SAMN05421538_102375 | Hypothetical protein. | 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.655 |
SDE84105.1 | SDD31131.1 | SAMN05421538_11284 | SAMN05421538_101339 | Glutaredoxin. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.603 |
SDE84105.1 | SDD42911.1 | SAMN05421538_11284 | SAMN05421538_101593 | Glutaredoxin. | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.863 |
SDE84105.1 | SDD65447.1 | SAMN05421538_11284 | SAMN05421538_102140 | Glutaredoxin. | Sulfide:quinone oxidoreductase. | 0.606 |
SDE84105.1 | SDE64744.1 | SAMN05421538_11284 | SAMN05421538_10921 | Glutaredoxin. | Hypothetical protein. | 0.863 |
SDE84105.1 | SDE84141.1 | SAMN05421538_11284 | SAMN05421538_11285 | Glutaredoxin. | Protein of unknown function. | 0.940 |