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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrBAspartate carbamoyltransferase; Annotation was generated automatically without manual curation; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (304 aa)    
Predicted Functional Partners:
pyrI
Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase.
 0.999
pyrC
Dihydroorotase, multifunctional complex type; Annotation was generated automatically without manual curation.
 0.999
EDP45842.1
Dihydroorotate dehydrogenase (dihydroorotate oxidase)(dhodehase) (dhodase) (dhod); Catalyzes the conversion of dihydroorotate to orotate.
 
 
 0.989
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
  
 0.986
pyrF
Orotidine 5'-phosphate decarboxylase; Annotation was generated automatically without manual curation; Belongs to the OMP decarboxylase family.
 
  
 0.981
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.932
EDP46634.1
Aspartate aminotransferase A (Transaminase A) (AspAT); Annotation was generated automatically without manual curation.
    
  0.890
asnB
Asparagine synthase (glutamine-hydrolyzing); Annotation was generated automatically without manual curation.
  
 
 0.675
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.
  
    0.670
guaA
Gmp synthase [glutamine-hydrolyzing] (glutamineamidotransferase) (gmp synthetase) (gmps); Catalyzes the synthesis of GMP from XMP.
 
  
 0.656
Your Current Organism:
Rickettsiella grylli
NCBI taxonomy Id: 59196
Other names: R. grylli
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