STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
radCDNA repair protein RadC; Annotation was generated automatically without manual curation; Belongs to the UPF0758 family. (224 aa)    
Predicted Functional Partners:
mreC
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
  
  
 0.731
EDP45825.1
Protein GntX; Annotation was generated automatically without manual curation.
 
    0.728
rpmB
Conserved domain protein; Annotation was generated automatically without manual curation; Belongs to the bacterial ribosomal protein bL28 family.
     
 0.648
rpmG
Ribosomal protein L33; Annotation was generated automatically without manual curation; Belongs to the bacterial ribosomal protein bL33 family.
       0.631
EDP46454.1
DNA internalization-related competence protein ComEC/Rec2; Annotation was generated automatically without manual curation.
 
  
 0.603
EDP46395.1
Thymocyte nuclear protein 1 (Thymocyte protein Thy28) (mThy28); Annotation was generated automatically without manual curation.
       0.561
EDP46198.1
Protein smf (DNA-processing chain A); Annotation was generated automatically without manual curation.
  
  
 0.487
recA
Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
  
 0.482
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.481
EDP45764.1
Sensory box histidine kinase/response regulator; Annotation was generated automatically without manual curation.
 
    0.459
Your Current Organism:
Rickettsiella grylli
NCBI taxonomy Id: 59196
Other names: R. grylli
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.