STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sucAOxoglutarate dehydrogenase (succinyl-transferring), E1 component; Annotation was generated automatically without manual curation. (929 aa)    
Predicted Functional Partners:
sucB
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 0.999
lpdA
Dihydrolipoyl dehydrogenase; Annotation was generated automatically without manual curation.
  
 0.996
sucC
succinyl-CoA synthetase beta chain (SCS-beta); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 0.994
EDP46993.1
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Annotation was generated automatically without manual curation.
 0.986
icd
Isocitrate dehydrogenase, NADP-dependent; Annotation was generated automatically without manual curation.
   
 
 0.983
EDP46478.1
Dihydrolipoamide acyltransferase; Annotation was generated automatically without manual curation.
 
 0.979
sdhA
Succinate dehydrogenase, flavoprotein subunit; Annotation was generated automatically without manual curation; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 
 0.976
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 0.974
EDP46252.1
Pyruvate dehydrogenase E1 component subunit beta (Scomplex, 36 kDa subunit); Annotation was generated automatically without manual curation.
   
 0.960
EDP46648.1
Succinate dehydrogenase iron-sulfur subunit; Annotation was generated automatically without manual curation; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
 
 
 0.944
Your Current Organism:
Rickettsiella grylli
NCBI taxonomy Id: 59196
Other names: R. grylli
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