Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
erpAHesB/YadR/YfhF family protein; Required for insertion of 4Fe-4S clusters for at least IspG. (133 aa)    
Predicted Functional Partners:
EDP46793.1
SUF system FeS assembly protein, NifU family; Annotation was generated automatically without manual curation.
  
 
 0.861
EDP45906.1
Glycine cleavage T protein; Annotation was generated automatically without manual curation; Belongs to the GcvT family.
  
 
 
 0.832
EDP46691.1
Putative glutaredoxin homolog; Annotation was generated automatically without manual curation; Belongs to the glutaredoxin family. Monothiol subfamily.
  
 0.632
djlA
DnaJ domain protein; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
  
 
 0.617
sufD
FeS assembly protein SufD; Annotation was generated automatically without manual curation.
  
 
 0.549
ispG
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.
     
 0.543
EDP46855.1
Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
  
   
 0.537
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 
 0.535
EDP46170.1
Putative lipoprotein; Annotation was generated automatically without manual curation.
       0.523
EDP46961.1
Conserved domain protein; Annotation was generated automatically without manual curation.
       0.523
Your Current Organism:
Rickettsiella grylli
NCBI taxonomy Id: 59196
Other names: R. grylli
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