Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EDP46363.1Cytosol aminopeptidase family protein; Annotation was generated automatically without manual curation; Belongs to the peptidase M17 family. (468 aa)    
Predicted Functional Partners:
pepN
Annotation was generated automatically without manual curation.
   
 0.874
gshB
Glutathione synthase; Annotation was generated automatically without manual curation; Belongs to the prokaryotic GSH synthase family.
   
 
 0.871
pepA
Cytosol aminopeptidase (Leucine aminopeptidase) (LAP)(Leucyl aminopeptidase) (Aminopeptidase A/I); Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
  
  
 
0.862
EDP46634.1
Aspartate aminotransferase A (Transaminase A) (AspAT); Annotation was generated automatically without manual curation.
   
  0.845
glyA-2
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
   
 
  0.820
EDP45872.1
Cystathionine gamma-lyase (Gamma-cystathionase)(Probasin-related antigen) (PRB-RA); Annotation was generated automatically without manual curation.
   
 
  0.820
EDP46775.1
Putative gamma-glutamylcysteine synthetase; Annotation was generated automatically without manual curation; identified by similarity to GB:AAB41630.1.
     
  0.819
EDP45731.1
Hypothetical protein; Annotation was generated automatically without manual curation; identified by glimmer; putative.
       0.773
ald
Alanine dehydrogenase; Annotation was generated automatically without manual curation; Belongs to the AlaDH/PNT family.
       0.773
alr
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
     
  0.715
Your Current Organism:
Rickettsiella grylli
NCBI taxonomy Id: 59196
Other names: R. grylli
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