STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LpdAKEGG: efa:EF1356 8.5e-174 lpdA; pyruvate dehydrogenase complex E3 component, dihydrolipoamide dehydrogenase K00382; Psort location: Cytoplasmic, score: 9.97. (468 aa)    
Predicted Functional Partners:
ESK66355.1
KEGG: efa:EF1355 2.6e-156 aceF; pyruvate dehydrogenase complex E2 component, dihydrolipoamide acetyltransferase K00627; Psort location: Cytoplasmic, score: 9.26.
 0.999
ESK66356.1
KEGG: efa:EF1354 6.0e-134 pdhB; pyruvate dehydrogenase complex, E1 component, beta subunit K00162.
 0.998
pdhA
Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 
 0.995
ESK66480.1
KEGG: bca:BCE_5130 1.1e-08 gcvH; glycine cleavage system protein H K00281.
    
 0.944
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.919
PflB
KEGG: lwe:lwe1422 0. pflB; formate acetyltransferase K00656; Psort location: Cytoplasmic, score: 9.26.
     
 0.905
GrcA
Glycine radical domain protein; KEGG: bat:BAS0481 3.5e-28 formate acetyltransferase K00656; Psort location: Cytoplasmic, score: 9.97.
     
 0.905
msrA-2
Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
 0.896
GlnA
KEGG: efa:EF2159 7.9e-171 glnA; glutamine synthetase, type I K01915; Psort location: Cytoplasmic, score: 9.26.
  
 
 0.838
ESK64681.1
KEGG: msu:MS1058 1.1e-125 lplA; lipoate-protein ligase A K03800; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.759
Your Current Organism:
Abiotrophia defectiva
NCBI taxonomy Id: 592010
Other names: A. defectiva ATCC 49176, Abiotrophia defectiva ATCC 49176, Abiotrophia defectiva str. ATCC 49176, Abiotrophia defectiva strain ATCC 49176
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