STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESK66149.1KEGG: spd:SPD_1560 3.4e-28 HAD superfamily protein (subfamily IIIA) phosphatase K01112. (174 aa)    
Predicted Functional Partners:
YqeH
Ribosome biogenesis GTPase YqeH; KEGG: vvu:VV1_1285 1.4e-05 predicted GTPase K06949; Psort location: Cytoplasmic, score: 8.96.
  
  
 0.872
YhbY
RNA-binding protein, YhbY family; KEGG: bhe:BH11070 0.0076 uvrD; DNA helicase II K03657.
  
  
 0.868
ESK66145.1
Hydrolase, HD family; KEGG: mmo:MMOB2760 1.3e-17 nadD; hypothetical protein K00969.
 
  
 0.816
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
    0.738
rsfS
Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
  
 0.696
ESK66143.1
Methyltransferase domain protein; KEGG: lsa:LSA1388 9.9e-38 putative methyltransferase K00599.
       0.650
tmcAL
Hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
     
 0.610
ESK66622.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
 
     0.543
ESK66150.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
       0.529
ESK66141.1
Putative ACR; Psort location: Cytoplasmic, score: 8.96.
       0.467
Your Current Organism:
Abiotrophia defectiva
NCBI taxonomy Id: 592010
Other names: A. defectiva ATCC 49176, Abiotrophia defectiva ATCC 49176, Abiotrophia defectiva str. ATCC 49176, Abiotrophia defectiva strain ATCC 49176
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.