STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESK65927.1Thioesterase family protein; KEGG: lsa:LSA0644 2.8e-40 putative acyl-CoA thioester hydrolase K01073; Psort location: Cytoplasmic, score: 8.96. (185 aa)    
Predicted Functional Partners:
proS
proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
       0.785
ESK65929.1
Hypothetical protein.
       0.588
rpmE2
Ribosomal protein L31.
  
    0.504
LepB
Signal peptidase I; KEGG: bld:BLi00675 3.4e-35 sipS; signal peptidase I; RBL03347 K03100; Psort location: CytoplasmicMembrane, score: 9.82; Belongs to the peptidase S26 family.
  
    0.407
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.405
ESK64876.1
Hypothetical protein; KEGG: gme:Gmet_0780 0.0012 MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor K03412:K00575.
     
 0.400
Your Current Organism:
Abiotrophia defectiva
NCBI taxonomy Id: 592010
Other names: A. defectiva ATCC 49176, Abiotrophia defectiva ATCC 49176, Abiotrophia defectiva str. ATCC 49176, Abiotrophia defectiva strain ATCC 49176
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.