STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LepB-2Signal peptidase I; KEGG: gka:GK1203 2.4e-36 type I signal peptidase K03100; Psort location: CytoplasmicMembrane, score: 9.82; Belongs to the peptidase S26 family. (199 aa)    
Predicted Functional Partners:
LepB
Signal peptidase I; KEGG: bld:BLi00675 3.4e-35 sipS; signal peptidase I; RBL03347 K03100; Psort location: CytoplasmicMembrane, score: 9.82; Belongs to the peptidase S26 family.
  
  
 
0.907
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
 
  
 0.832
ESK65396.1
Peptidase, S41 family; KEGG: bli:BL01439 3.7e-93 ctpA; carboxy-terminal processing protease K03797; Belongs to the peptidase S41A family.
 
   
 0.823
deoD
KEGG: lin:lin1970 9.8e-70 deoD; purine nucleoside phosphorylase K03784; Psort location: Cytoplasmic, score: 8.96.
       0.699
ESK65398.1
Hypothetical protein; KEGG: spz:M5005_Spy_0383 2.2e-10 D-alanyl-D-alanine carboxypeptidase K01286; Belongs to the UPF0346 family.
       0.673
YlqF
Ribosome biogenesis GTP-binding protein YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
  
    0.667
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
 
 
 0.622
ESK66072.1
Hypothetical protein; KEGG: mpu:MYPU_1770 1.3e-26 cysS; cysteinyl-tRNA synthetase K01883; Psort location: Cytoplasmic, score: 8.96; Belongs to the UPF0374 family.
      0.576
ESK65399.1
Channel protein, hemolysin III family; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.559
ESK65062.1
LPXTG-motif protein cell wall anchor domain protein; KEGG: ehi:13.t00009 1.9e-12 phosphatidylinositol-4-phosphate 5-kinase, putative K00889.
  
  
 0.543
Your Current Organism:
Abiotrophia defectiva
NCBI taxonomy Id: 592010
Other names: A. defectiva ATCC 49176, Abiotrophia defectiva ATCC 49176, Abiotrophia defectiva str. ATCC 49176, Abiotrophia defectiva strain ATCC 49176
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.